Friday, September 30, 2011

Proteolytic enzymes such as bounced back, Wobenzyn & Chymotrate should only be taken on an empty stomach.
Read "My Thoughts on Natural Vitamins in 2011" on my web http://bit.ly/n9Yr95 by Dr. Rob Sinnott. Share it, like it & enjoy it.

Thursday, September 29, 2011

I don't use expensive fruit juices with 90%+water. Aloe leaf is 98.5% water & freeze drying to a concentrated power gets the MICHALIS-MENTEN phenomenon.
Your vitamin C is it synthetic man-made coal tar? Synthetic forms are Ascorbic acid, calcium ascorbate and sodium ascorbate.
Our skin has holes in it. People often make their skin harmful to their body by adding toxins to it (perfume etc). http://tinyurl.com/6xdccvt read my new post & share it.

Wednesday, September 28, 2011

New post on scientific way to tell if vitamins are natural http://tinyurl.com/3m9afft "My Thoughts on Natural Vitamins in 2011"

My Thoughts on Natural Vitamins in 2011





I have been asked on many occasions to share my thoughts about naturally sourced vitamins and minerals, specifically why I prefer them when designing new product formulations. My thinking on this subject has evolved over several decades from the point where I assumed equivalency between naturals and synthetics, to where I am today. When I first started into analytical chemistry in the 1980s, it was accepted practice to use synthetic vitamins as the standard when analyzing and quantifying vitamins from both natural and synthetic sources. This was because the analytical methods commonly employed at the time were based on relatively simple chromatographic equipment that could not distinguish natural from synthetic. Both compounds co-eluted using these methods, so it was assumed that they must be the same. It didn’t occur to me (or others) at the time that this could be due to a limitation of our methods rather than an absolute “truth” about the equivalency of natural and synthetic vitamins.

This is how it is with science. Based on information and equipment that simply was not available when I developed my original thoughts on the subject, I now realize several factors that certainly could make a significant difference in how natural and synthetic vitamins perform in actual living beings. While these differences are still in the early stage of being defined, I personally believe that there is something important we have been missing, and it will not be a simple matter to sort it out. We have to accept that science is always a work in progress and what we may “know” about our technology at one time could be radically different several decades into the future because of factors that we didn’t know about or take into serious consideration.

Technology Now Distinguishes Natural and Synthetic Vitamins

The first thing that helped change my thinking about natural versus synthetic vitamins was the wider availability of better analytical technology. There are analytical machines readily available today, including those in Mannatech’s own R&D laboratory, that can blindly distinguish plant-sourced compounds from “bioidentical” compounds synthesized from fossil fuels such as coal tar or petroleum. These analytical machines are equipped with mass-selective detectors that can determine the ratio of isotopes in a particular compound. Carbon-based compounds such as vitamins and phytochemicals are all made up predominantly of two stable carbon isotopes (C12and C13) and one unstable isotope (C14), but the ratios differ depending on whether the material is derived from fresh plant material or from fossil fuel sources. Beyond this, we get into heavy chemistry. But suffice it to say that if we have two samples of a pure compound, such as beta-carotene, one of which is from a plant and the other synthesized from fossil fuels, it is possible to tell the difference. So, these two sources are not strictly identical as previously assumed. So the next question is, is this difference biologically important?

Organisms Distinguish Natural from Synthetic

Strictly speaking, the “chemistry” of an element is primarily dictated by the outer valence electrons of an atom. So, according to this thought, stable isotopes such as C12 and C13 should theoretically behave the same. In biological systems, there are some notable exceptions to this rule. A clear example of this occurs with the two major stable isotopes of hydrogen, which are “normal hydrogen,” with one proton, and deuterium, which has one proton and one neutron. Chemically, they should behave the same because they both have one valence electron, and in fact they do form analogous compounds with other elements. However, the way these compounds behave in biological systems can be very different. For example H20 (normal water) is chemically similar to D2O (heavy water) and behaves similarly under most conditions, but whereas H20 is non-toxic to living organisms, D2O at elevated concentrations above its natural abundance has toxicity toward plants and animals. Obviously, the complex metabolic processes present within living organisms do not see these stable isotopes as equivalent.

Another well-documented example of “isotopic discrimination” in living organisms involves the carbon isotopes C12 and C13. Certain types of plants such as cactus and other succulents have a unique type of photosynthesis called Crassulacean acid metabolism (CAM). This photosynthetic process, which has many steps, results in measurable enrichment of carbon isotopes and is thought to be due to the combined effects of diffusion and selective affinity of certain enzymes for specific carbon isotopes. First discovered in the plant kingdom in the early 1970s and more thoroughly studied in subsequent decades, this example shows that discrimination of carbon isotopes by living organisms can, and does, actually have biological relevance.

Much more recently, it was found that human enzymes involved in normal metabolism can also have certain carbon isotope preferences. In a study by Ludke et al. published in the Journal of Lipid Research in 2008, it was found that HMGR, a major enzyme involved in the production of steroid hormones like estrogen and testosterone, showed a statistically measurable preference for C12 over C13. This taken with other evidence, such as the fact that the pool of lipids in the body is typically around 8% depleted in C13, suggests that, at least in some human biological processes such as lipid and steroid synthesis, carbon isotope discrimination is significant and is probably important. So does this prove for certain that natural, plant-derived vitamins function better in humans than those synthesized from fossil fuels? It does not. But it does put forward a new hypothesis that might further explain some of the results that were recently compiled [l1] regarding the performance of natural vitamins versus synthetics. As would be expected, the carbon isotope ratios of natural vitamins derived from recently harvested organisms are quite different from those of vitamins synthesized from fossil fuels. After all, fossil fuels have decomposed over millions of years under severe heat and pressure conditions, so they would be expected to be quite different in composition from organic compounds of contemporary origin.

Natural Vitamins Appear to Be Absorbed Better and Retained Longer

Admittedly, research specifically focusing on the advantages of natural vitamins is still quite young and the evidence is far from conclusive, but some interesting data is emerging. In a peer-reviewed article published in 2000 in the journal Medical Hypothesis, author R.J. Thiel summarizes some interesting data culled from numerous studies on naturally sourced vitamins. Some of his findings from animal studies include:

“Natural food complex vitamin B1 was absorbed 1.38 times more into the blood and was retained 1.27 times more [l2] in the liver than an isolated USP thiamin hydrochloride.”

“Natural food complex vitamin B2 was absorbed into the blood and was retained 1.92 times more in the liver than an isolated USP riboflavin.”

“Natural food complex niacinamide is 3.94 times more absorbed in the blood than USP niacinamide and 1.7 times more retained in the liver than isolated USP niacinamide.”

“Natural food complex B6 was absorbed 2.54 times more into the blood and was retained 1.56 times more in the liver than an isolated USP form.”

“Natural food complex folate was absorbed only 1.07 times more into the blood, yet was retained 2.13 times more in the liver than isolated USP folic acid.”

“Natural food complex vitamin B12 was absorbed 2.56 times more into the blood and was retained 1.59 times more in the liver than isolated USP cyanocobalamin.”

Numerous ideas have been put forward about why natural, food-sourced vitamins may have better absorption and retention than purified synthetics have. It is known to be the case that with many naturally sourced vitamins the vitamins are complexed with other naturally occurring “impurities” such as natural fats, oils or phytochemicals. These naturally occurring complexes are known in some cases to enhance the biological absorption and/or retention of vitamins over purified, single-component compounds. This makes perfect sense since vitamin complexes in living organisms must remain soluble, while synthetic vitamins crystallized out of a solvent mixture during a chemical process can have a wide range of solubility.

In summary, I believe that there are some performance differences between natural and synthetic vitamins. These differences are perhaps based on multiple scientific factors, some of which haven’t been considered up to this point and none of which have been explored thoroughly. It’s not alchemy and it’s not quackery. It’s just a branch of science that is fresh and new and important, much like genetics was in the ‘70s and glycobiology was in the ’90s. Science aside, I have found that when consumers are aware that there is a choice between naturally sourced vitamins and synthetic vitamins, they overwhelmingly prefer the natural vitamins. Their decisions may be based on some scientific knowledge or they may be based on intuition alone. I haven’t done that research yet, but one thing is clear: The consumer has a preference for natural vitamins, and it’s always good business to meet the consumer’s needs and desires—especially when you can be unique in doing so.

Dr. Rob Sinnott

Dr. Rob Sinnott is Co-CEO and Chief Science Officer for Mannatech, Incorporated.

Tuesday, September 27, 2011

I love my work helping people & my office. I love my work, Love my Wife (Dottie), Church & family. "2 blessed to be depressed."

Monday, September 26, 2011

Friday, September 23, 2011

Vitamins at 350°for 10 minutes



See what happens to vitamins supplements if they are not natural when you put them in the oven at 350°for 10 minutes.
When we put food in the oven it turns brown and so should your vitamins but if black stuff comes out of them it's obvious there not natural they are petroleum coal tar derivatives. Take a look at the pictures I posted and then try it with your vitamins. Let me know how it turns out OK?

http://tinyurl.com/3d2bclt

Wednesday, September 21, 2011

Dietary Guidelines: The USDA Makes It Simple, Mannatech Makes It Complete


Dietary Guidelines: The USDA Makes It Simple, Mannatech Makes It Complete Mannatech Research and Development Team
In 1977, when the U.S. Senate Select Committee on Nutrition and Human Needs issued “Dietary Goals for the United States,” their primary goal was to discourage excessive intake of food components linked to chronic disease. This was the first of many governmental attempts to influence America’s dietary choices. It can be argued that subsequent confusing political- and industry-driven food guides (1), including the well-known Food Guide Pyramid, actually contributed to the predicament we find ourselves in today: skyrocketing obesity and increased incidence of diseases associated with poor dietary choices. Today, about 1/3 of American adults are obese (2), and five of the 15 leading causes of death in the U.S. have a significant dietary component (http://www.cdc.gov/nchs/data/nvsr/nvsr59/nvsr59_04.pdf).
What Is On Your Plate?
Considering the magnitude of the problem, the United States Department of Agriculture’s (USDA) 2010 dietary guidelines, “Choose My Plate,” is a small, but encouraging step in the right direction (http://www.choosemyplate.gov). This simple image can serve as a great breakfast, lunch and dinner reminder for everyone. Just look at your plate and ask yourself: is it half-full of fruits and vegetables? If so, you’re halfway there! Add some lean protein and whole grains with a little dairy on the side, and you can sit back and enjoy your meal, guilt-free!

Even if we do remember this simple image, many of us will still find it difficult to fill our plates with the best foods at every meal. Because many health and nutrition experts understand this, they also recommend daily, judicious use of dietary supplements.(3),(4)
With My Plate in mind, we suggest that the USDA’s message be taken one step further: to best support optimal health, include a daily intake of Mannatech’s dietary supplements based on Real Food Technology® solutions. A good starting point would be our Real [4] for LifeSM products (see line-up below) plus our new, Omega-3 with Vitamin D3:
[1] Ambrotose® powder: glyconutrients for cellular communication and immune, brain and gastrointestinal health*
[2] PhytoMatrix® caplets: natural food-sourced vitamin/mineral/phytonutrient supplement*
[3] Ambrotose AO® capsules: the most effective antioxidant supplement on the market today*
[4] PLUS™ caplets: for endocrine, breast, prostate, cardiovascular, bone and colon health*
Omega-3 with Vitamin D3: for brain, bone and heart health; supports a healthy inflammatory response*
Excellent food choices plus the best quality supplements on the market today equals the MannatechPlate!

For those who want more specifics about science-based dietary/lifestyle choices, Harvard University’s Walter Willet and Patrick Skerrett’s Healthy Eating Pyramid is a great choice (www.thenutritionsource.org) of material. Note that their pyramid indicates that most people would benefit from dietary supplements!
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
1. Nestle M. Food Politics. Berkeley, CA: University of California Press, 2002.
2. Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010;303:235–41.
3. Fletcher RH, Fairfield KM. Vitamins for chronic disease prevention in adults: clinical applications. JAMA 2002;287:3127–9.
4. Willett W, Stampfer M. Rebuilding the Food Pyramid. Scientific American 2003;64–71.

Wednesday, September 7, 2011

Synthetic Vitamin A Side Effects

Vitamin A Palmitate Side Effects

Vitamin A palmitate is a more stable, synthetic version of the essential nutrient vitamin A joined to palmitic acid. Vitamin A palmitate is the form used to fortify foods and skin moisturizers. The U.S. Food and Drug Administration says it is generally regarded as safe. The FDA reports the lowest dose for side effects is a total vitamin A intake of 700 to 1,000 IU/kg per day over several months. In comparison, the recommended dietary allowance for adults is 50 IU/kg per day. The typical Western diet does not approach toxic levels of vitamin A unless large doses are taken as supplements.
Skin Effects
Vitamin A in its natural form of retinol is a common ingredient in topical creams marketed as wrinkle reducers or acne medications. In high doses taken by mouth, it causes dry, itchy or peeling skin on the lips and palms. Yellow-orange patches may appear on the soles of the feet, palms of the hands or on the skin around the nose and lips. Skin can become increasingly sensitive to sunlight at high doses. Hair loss is another side effect of taking toxic levels of total vitamin A.
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Body Pain
The severity of pain or illness experienced with ingesting high amounts of vitamin A varies with the dose. General weakness, joint and bone pain ranges from mild to disabling.
General Malaise
People taking high doses of vitamin A experience nonspecific symptoms. MayoClinic.com notes that general feelings of discomfort including headache, irritability, dizziness, fatigue and unusual excitability are reported. Double vision and convulsions are rare events that should be reported immediately to a doctor.
Stomach Effects
Stomach pain, loss of appetite, nausea and vomiting are common side effects of ingesting large amounts of vitamin A.
Internal Organs
MayoClinic.com reports that the liver and spleen can become enlarged with high vitamin A intake. People with liver disease risk developing intrahepatic cholestasis, a condition where bile can no longer flow into the intestines. Symptoms include intense itching--especially of the feet and hands, dark colored urine, light colored stool and increased frequency of urination or amount of urine passed.
Birth Defects Pregnant women who consume toxic levels of vitamin A increase the risk of birth defects in their unborn child. The FDA reports that laboratory animals fed high doses of vitamin A experience abortions or malformation of the central nervous system of the developing fetus. Vitamin A is excreted in breast milk. Infants exhibit a bugling fontanel or soft spot and brain pressure from ingesting high levels of vitamin A.
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References
FDA: Vitamin A Palmitate
MayoClinic.com: Vitamin A
MayoClinic.com: Vitamin A Basics
Vitamins and Health Supplements Guide: Vitamin A Palmitate

Read more: http://www.livestrong.com/article/242429-vitamin-a-palmitate-side-effects/#ixzz1XKZ4es2v

About this Author
Diane Hauze started writing restaurant reviews in suburban Philadelphia in 2007. She has been published on Philly.com and has experience in applied research in the pharmaceutical industry. Hauze holds a Ph.D. in chemistry from the University of Pennsylvania.


Read more: http://www.livestrong.com/article/242429-vitamin-a-palmitate-side-effects/#ixzz1XKbJgVcx